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Search Results for " vx 445 "

2

Compounds

Cat No. Product Name Synonyms Targets
T14935 Elexacaftor VX-445 CFTR , Autophagy
Elexacaftor (VX-445) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR) and it also facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface.
T78240 (R)-Elexacaftor (R)-VX-445 CFTR
(R)-Elexacaftor, an enantiomer of Elexacaftor, functions as a modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It exhibits an EC50 of 0.29 µM for the CFTR dF508 mutation [1].
TargetMol